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O‑rings for biopharmaceutical applications

Effective sealing for all types of biopharmaceutical processing equipment.

  • Biopharmaceutical

High purity O-rings are an exceptionally versatile sealing device and the world's most popular volume-produced seal. James Walker has been making high specification, high purity O-rings for the biopharmaceutical market since 2010 and our international customers include virtually every biopharmaceutical manufacturer and many global OEMs who depend on high purity O-rings from James Walker in the safe and effective manufacture of therapeutic product.

We maintain an inventory of over one million O-rings in commonly used sizes and materials, available for same-day shipping. Additionally, with a stock of more than 10,000 moulds we can typically provide non-standard high purity O-rings in a matter of days. We also offer the option to design custom high purity O-ring profiles like D seals to fulfill specific customer needs.

Our high purity O-rings are manufactured from our industry-leading Elast-O-Pure materials, including EP75B and SIL70.

Elast-O-Pure EP75B is specifically designed for use in biopharmaceutical environments. These O-rings are certified to meet USP Class VI standards and are made from ethylene-propylene-diene terpolymer, featuring exceptionally low extractable substances. They are characterised by their minimal compression set, ensuring durable and long-lasting sealing performance. Importantly, these O-rings are entirely free of Animal Derived Ingredients (ADI) and showcase impressive resistance to both SIP (Steam-in-Place) and CIP (Clean-in-Place) processes, making them an excellent choice for various applications.

Elast-O-Pure SIL70 is produced from platinum-cured translucent silicone (VMQ) and boasts a range of valuable attributes. It is certified to meet the stringent USP Class VI standards and is composed of material that is completely free of Animal Derived Ingredients (ADI). Additionally, this silicone material demonstrates a low compression set, ensuring reliable and long-lasting sealing performance. It further excels in high-temperature resistance, making it a versatile choice suitable for a wide array of critical applications.

These high purity O-rings in Elast-O-Pure EP75B and SIL70 materials are ideal for critical applications, particularly in biopharmaceutical settings where purity and performance are paramount.


Hygienic clamp gaskets

USP Class VI clamp gaskets manufactured in EPDM and silicone elastomers specifically formulated for biopharmaceutical applications.

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Hygienic clamp gaskets

High purity O-rings play a crucial role in global pharmaceutical manufacturing

James Walker's high purity O-rings play a crucial role in global pharmaceutical manufacturing, supporting a wide range of applications. From serving as probe holders in bioreactors to being integral components in filtration systems during downstream processing, these O-rings are instrumental in ensuring the quality and reliability of drug production on a global scale. In the biopharmaceutical industry, it is imperative that product contact parts adhere to the most stringent standards. Our high purity O-rings and tri-clamp seals not only meet but surpass industry benchmarks, outperforming our competitors in terms of both quality and performance.

High purity O-rings from James Walker, contributing to production efficiency

By specifying James Walker's Elast-O-Pure high purity O-rings, sites can proactively prevent a range of issues, including excessive maintenance costs, unplanned downtime, batch contamination, and unnecessary investigations. These high purity O-rings ensure a reliable and trouble-free operation, ultimately leading to more efficient and cost-effective processes.

These high purity O-rings play a pivotal role in preventing batch contamination, a critical concern in the pharmaceutical and biopharmaceutical industries. Ensuring the integrity of each batch not only safeguards product quality but also upholds regulatory compliance, reducing the need for time-consuming and costly investigations.

Specifying James Walker's Elast-O-Pure high purity O-rings offers a comprehensive solution to multiple challenges within the industry, promoting seamless operations, cost savings, and peace of mind for businesses in the pharmaceutical and biopharmaceutical sectors.

Discover more about the range of high purity O-rings from James Walker

For detailed information and inquiries regarding our world-leading high purity O-rings designed specifically for the biopharmaceutical industry, please don't hesitate to get in touch with your local James Walker office. Our team is readily available to provide you with the information and support you need to make informed decisions and optimise your operations.

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Want to discuss your project, engineering or materials challenge expert to expert? Simply provide us with your contact details and a little information about the application you are working on, and one of our experts will contact you as soon as possible.

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